Objective: To promote establishment of a unified food and drug safety emergency management and disposal system in Zhejiang Province and to provide an empirical basis for establishing a reasonable and effective emergency management system. Methods: An empirical investigation and analysis of the emergency management status, human resources and hardware equipment resources of the food and drug supervision and administration institutions at city and county level were conducted through the sampling survey. Results: At present, the number of emergency management personnel in the food and drug supervision institutions of cities and counties of Zhejiang Province was relatively insufficient, and training of professional knowledge was relatively weak. As far as the emergency management equipment was concerned, few basic hardware facilities and equipment were equipped, and related software or system construction of emergency management was more backward. Conclusion: It was suggested that the human resources investment of the food and drug safety emergency management should be increased, on the job training of the emergency management personnel should be strengthened and the knowledge structure should be optimized. Both the level of basic equipment of emergency management and the emergency management information system should be gradually improved. Food and drug emergency management collaborative plan should be implemented to enhance the collaboration of various departments.