Research Progress

Research Progress of the Structure and Biological Activities of Iridoids Compounds

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  • (1)National Institutes for Food and Drug Control, Beijing 100050, China;Beijing University of Chinese Medicine, Beijing 100029, China; (2)National Institutes for Food and Drug Control, Beijing 100050, China; (3)Beijing University of Chinese Medicine, Beijing 100029, China

Online published: 2019-03-22

Abstract

Objective:To summarize in details the newly discovered iridoids compounds with new structural features and their biological activities and to provide new ideas for the study of the structural activities of iridoids compounds. Methods:The literatures of the new compounds of iridoids published in the past 30 years at home and abroad were reviewed and summarized, and the research status of their structures and biological activities were summarized. Results:The main structures of iridoids compounds were iridoid glycosides, secoiridoids and iridoid esters. The main clinical biological activities of iridoids compounds included neuroprotective, antitumor and hepatoprotective effects. Conclusion:Iridoids compounds are widely distributed and have great medicinal values. Through the summary and analysis of the structure and biological activities of iridoids compounds, the relationship between the structures and activities of iridoids compounds was explored in order to provide literature and data support for drug development and utilization.

Cite this article

Wang Feifei, Zhang Yumei, Zheng Xiaowei, Dai Zhong, Liu Bin, Ma Shuangcheng . Research Progress of the Structure and Biological Activities of Iridoids Compounds[J]. Chinese Pharmaceutical Affairs, 2019 , 33(3) : 323 -330 . DOI: 10.16153/j.1002-7777.2019.03.014

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