Enterococcus is currently a research hotspot for probiotics and is used in a variety of microecological preparations and plays an important role in the treatment and prevention of various diseases such as gastrointestinal diseases. However, enterococcus may convert to pathogenic bacteria under certain conditions. According to some reported clinical data, some of nosocomial infections are caused by enterococcus. In view of the probiotic and potential pathogenic risk of enterococcus, it is urgent to evaluate the safety of enterococcus. At present, most domestic and foreign researches mainly evaluated the safety of enterococcus in terms of drug resistance and virulence factors. Some studies have also investigated the safety of enterococcus through animal experiments. All results showed that no safety problem of probiotic enterococcus has been found.
Lu Xu, Zhang Ying, Zeng Ming
. Research Progress and Regulation of Safety Evaluation of Probiotic Enterococcus[J]. Chinese Pharmaceutical Affairs, 2019
, 33(5)
: 555
-560
.
DOI: 10.16153/j.1002-7777.2019.05.009
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