目的：建设落实好质量管理体系，确保实验室报告的准确性和可靠性，维护客户的切身利益，维护实验室的公正性和权威性。方法：实行质量责任“网格化”，实验室管理“程序化”，检验检测全过程“痕迹化”，质量监督考核“常态化”，实验室平台建设“信息化”（以下简称“五化管理新模式”）。结果：“五化管理新模式”在实验室近2年的应用中，国家和省级的能力验证均获得“结果满意”，客户的检验检测报告结果差错申诉为零。结论：需求和资源是变化的,持续改进是永恒的；用“五化管理新模式”提升实验室质量管理水平，具有可操作性、实用性、有效性。“五化管理新模式”对更好的适应新常态监管很有必要性。

Objective: To construct and implement the quality management system, ensure accuracy and reliability of laboratory results, maintain the vital interests of customers and the fairness as well as authority of laboratory. Methods: The gridding of quality responsibility, the routinization of laboratory management, the trace of inspection and testing process, the normalization of quality supervision and inspection, and the informatization of laboratory platform construction, known as "five new patterns of management", were implemented. Results: The results of national and provincial proficiency tests were satisfying without customer's complaints about the errors of inspection and testing report during the 2-year-application of "five new patterns of management" in laboratory. Conclusion: The demand and resources are changing but the continuous improvement is eternal. Using "five new patterns of management" to enhance the laboratory quality management level is operable, practical and effective. It is necessary to carry out "five new patterns of management" in order to better adapt to the new normal regulation.